Clinical studies on Hepatic Coma of 102 Patients.

Drug-induced hypoglycemic coma in 102 diabetic patients.

BACKGROUND Hypoglycemic coma is a continuous threat for diabetic patients treated with insulin and/or oral hypoglycemic agents; it may be associated with substantial morbidity and mortality. METHODS We retrospectively reviewed our clinical experience with drug-induced hypoglycemic coma during a 7-year period. RESULTS The study consisted of 102 patients and included 61 females and 41 males. ...

The mechanism of hepatic coma.

Hepatic coma: the electroencephalographic pattern.

Recent advances in our knowledge of the neurophysiologic mechanisms underlying sleep and experimental states of coma (1) suggest the need for a neurophysiologic approach to the many complex clinical syndromes associated with disturbance of consciousness. The coma syndrome associated with hepatic disease and usually known as hepatic coma was chosen for investigation since it presents a good exam...

Ammonia Intoxication in Hepatic Coma

Blood ammonia nitrogen was determined in 36 cases of hepatic coma and 63 cases of liver disease. Significant elevations (PL 0.001) were noted in coma due to hepatitis and cirrhosis and the mortality rate was 89% and 9 1.3% respectively. Raised ammonia nitrogen in hepatic coma is a sign of grave prognosis (JPMA 34 : 9, 1984).

Disorders of renal function in hepatic coma.

Renal failure is a frequent complication in advanced liver disease (Conn, 1973; Papper, 1978). Gastrointestinal bleeding and forced diuresis may be the causes in fulminant hepalic. failure and cirrhosis (Hecker and Sherlock, 1956; Shear et al., 1965). Hepatic coma or an associated metabolic abnormality may affect renal function or aggravate pre-existing renal abnormalities in severe liver disea...